4-Bromophenylzinc iodide
4-Bromophenylzinc iodide
CAS: 148651-39-2
Molecular Formula: C6H4BrIZn
4-Bromophenylzinc iodide - Names and Identifiers
4-Bromophenylzinc iodide - Physico-chemical Properties
| Molecular Formula | C6H4BrIZn |
| Molar Mass | 348.29 |
| Density | 1.045g/mLat 25°C |
| Flash Point | -17°C |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
4-Bromophenylzinc iodide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S33 - Take precautionary measures against static discharges. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2056 3/PG 2 |
| WGK Germany | 1 |
| Hazard Class | 4.3 |
4-Bromophenylzinc iodide - Introduction
4-Bromophenylzinc iodide is an organic zinc compound with the chemical formula C6H4BrIZn. It is a white solid, usually in the form of an organic solvent.
4-Bromophenylzine iodide has important applications in organic synthesis. It can be used as an organometallic reagent and can participate in a variety of organic synthesis reactions such as cross-coupling reactions and reduction reactions. It is often used to introduce bromo and iodo groups in reactions that build carbon-carbon and carbon-nitrogen bonds. In addition, it can also be used to prepare chiral enteric modification of compounds.
A common method for preparing 4-Bromophenylzinc iodide is obtained by reacting 4-bromoiodobenzene with metal zinc in chloroform or dimethylformamide (DMF). Metallic zinc is first reacted with iodine to form zinc bromide, and then reacted with 4-bromophenylzinc iodide to give 4-Bromophenylzinc iodide.
Regarding safety, 4-Bromophenylzinc iodide may cause irritation to the human body and is flammable. It is necessary to avoid contact with open flames. Appropriate protective measures should be taken during operation, such as wearing protective gloves and goggles, and operating in a well-ventilated environment. In addition, it should also be stored in a sealed container, away from heat and fire sources.
4-Bromophenylzine iodide has important applications in organic synthesis. It can be used as an organometallic reagent and can participate in a variety of organic synthesis reactions such as cross-coupling reactions and reduction reactions. It is often used to introduce bromo and iodo groups in reactions that build carbon-carbon and carbon-nitrogen bonds. In addition, it can also be used to prepare chiral enteric modification of compounds.
A common method for preparing 4-Bromophenylzinc iodide is obtained by reacting 4-bromoiodobenzene with metal zinc in chloroform or dimethylformamide (DMF). Metallic zinc is first reacted with iodine to form zinc bromide, and then reacted with 4-bromophenylzinc iodide to give 4-Bromophenylzinc iodide.
Regarding safety, 4-Bromophenylzinc iodide may cause irritation to the human body and is flammable. It is necessary to avoid contact with open flames. Appropriate protective measures should be taken during operation, such as wearing protective gloves and goggles, and operating in a well-ventilated environment. In addition, it should also be stored in a sealed container, away from heat and fire sources.
Last Update：2024-04-10 22:29:15
